Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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Identifying Susceptibility Genes for Prostate Cancer--A Family The latter observation has motivated the search for prostate cancer susceptibility genes by many research groups around the world for the past decade. Prostate Cancer Gene Discovered Prostate Cancer Gene Discovered. A newly discovered genetic variant appears to carry with it a significant risk for prostate cancer, putting about one man GEArray^ Q Series Mouse Androgen Signaling and Prostate Cancer GEArray^ Q Series Androgen Signaling and Prostate Cancer Gene Array is designed to assess the role of 96 genes in androgen-regulated processes that are TGen finds key prostate cancer gene Scientists from TGen and other research facilities and universities have identified a gene that may be linked to an aggressive form of prostate cancer, genome.gov | 1998 Release: Prostate CA Gene Mapped to X Chromosome It is the second prostate cancer gene this group of scientists has uncovered. Their report appears in the October issue of Nature Genetics. U-M scientists say fused genes trigger prostate cancer development U-M researchers detected the unique molecular signature of the fused genes in the majority of prostate cancer tissue samples they analyzed, Looking for Prostate Cancer Genes If increased sharing of these markers is found, then the regions may contain genes for prostate cancer susceptibility or aggressiveness. Localization of a Prostate Cancer Predisposition Gene to an 880-kb In conclusion, there exists substantial evidence from multiple independent studies for a predisposition gene for prostate cancer at chromosome 22q12.3. Prostate Cancer and Gene Therapy : Molecular Therapy This web focus, presented by Molecular Therapy , highlights some important research that has advanced the field of prostate cancer gene therapy. ACS :: Prostate Cancer Gene Discovery May Aid Testing Scientists have confirmed the existence of a gene for prostate cancer, paving the way for possible testing and providing clues that may one day lead to a Gene Rearrangements Found in Prostate Cancer - National Cancer A new study, using a unique detection method, has led scientists to identify several genes whose rearrangements in prostate cancer cells may play a role in Researchers Find Mutation In Prostate Cancer Gene "Our results suggest that this gene is involved in prostate cancer," says Timothy Rebbeck, PhD, assistant professor of epidemiology and principal Prostate Cancer Thus far, the search for prostate cancer genes resulted in the So far, six potential prostate cancer genes are reported in the literature. BBC News | HEALTH | Prostate cancer gene identified Scientists have identified a gene which they believe is linked to an inherited form of prostate cancer. Gene Linked To Aggressive Prostate Cancer, Study Finds Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive BBC NEWS | Health | Prostate cancer gene identified Scientists have identified a gene which could identify how aggressive a man's prostate cancer will be. New Prostate Cancer Gene Identified Researchers at the Translational Genomics Research Institute (TGen) have found a new way to speed the discovery of genes that suppress tumors, Prostate cancer THE SECOND LEADING cause of cancer death in American men, prostate cancer 1 in 500 cases of prostate cancer. The next step will be to clone the gene. OMIM - PROSTATE CANCER Clinical Synopsis · Gene map · Entrez Gene · Nomenclature |
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