Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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Gene Expression in Prostate Cancer | Applied Genetics News | Find Gene Expression in Prostate Cancer from Applied Genetics News in Health provided free by Find Articles. Gene Expression Data Portal (GEDP) 2002, 62(15):4499-506, Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic Dana-Farber/Harvard Cancer Center: Project 4: Gene Expression of The overall goal of Project 4 is the development of a gene expression-based predictor of outcome in prostate cancer. The hypothesis underlying this project Broad Institute Cancer Program Publications Gene Expression Correlates of Clinical Prostate Cancer Behavior Keywords, oligonucleotide array; oncology; prostate cancer; gene expression IngentaConnect Androgen-regulated gene expression in prostate cancer Androgen-regulated gene expression in prostate cancer. Authors: Trapman J.; Cleutjens K.B.J.M.. Source: Seminars in Cancer Biology, Volume 8, Number 1, NGFN: Prostate cancer: Gene expression signature for improved Extraction and processing of high quality RNA from impalpable and macroscopically invisible prostate cancer for microarray gene expression analysis. IngentaConnect ICI 182780Regulated Gene Expression in DU145 ICI 182780-Regulated Gene Expression in DU145 Prostate Cancer Cells Is Mediated by Estrogen Receptor-b/NFjB Crosstalk. Authors: Leung, Yuet-Kin1; Gao, University of Pittsburgh Microarray Dataset Collection Latil A, Bieche I, Chene L, Laurendeau I, Berthon P, Cussenot O, Vidaud M. Gene expression profiling in clinically localized prostate cancer: a four-gene Prostate Cancer and Prostatic Diseases - Table 1 for article Prostate cancer-associated gene expression alterations defined by ChipInspector and Bibliosphere analysis. Figure and tables index Cancer Letters : Gene expression in the LNCaP human prostate Gene expression in the LNCaP human prostate cancer progression model: Progression associated expression in vitro corresponds to expression changes Cancer Cell -- Table of Contents (Mar 1, 2002, 1 (2)) Gene expression correlates of clinical prostate cancer behavior Dinesh Singh, Phillip G. Febbo, Kenneth Ross, Donald G. Jackson, Judith Manola, Alterations in Gene Expression Profiles during Prostate Cancer Se-P gene expression levels correlated well between the two tech-. niques. Correlation of Results to Changes in Human Prostate Cancer. Alterations in Gene Expression Profiles during Prostate Cancer To validate further the alterations in gene expression of two genes identified by microarray analyses with potential biological relevance to prostate cancer Gene expression alterations in prostate cancer predicting tumor Identification of the genes and patterns of gene expression will provide a more cohesive picture of prostate cancer biology. PATIENTS AND METHODS: In this Comprehensive gene expression analysis of prostate cancer reveals We performed a comprehensive gene expression analysis of prostate cancer using oligonucleotide arrays with 63175 probe sets to identify genes and expressed Gene expression profiling predicts clinical outcome of prostate Gene expression profiling predicts clinical outcome of prostate cancer. Gennadi V. Glinsky1, Anna B. Glinskii1, Andrew J. Stephenson2, Robert M. Hoffman3 BioMed Central | Full text | Differences in gene expression in Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors BioMed Central | Full text | Gene expression profiles of prostate Using gene expression microarrays, a number of studies have characterized expression profiles of prostate cancer, normal tissue and metastatic cancers. Gene Expression Alterations in Prostate Cancer Predicting Tumor PATIENTS AND METHODS: In this study, we performed a comprehensive gene expression analysis on 152 human samples including prostate cancer tissues, |
| prostate cancer gene expression |
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