Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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CiteULike: Docetaxel Plus Prednisone or Mitoxantrone Plus Docetaxel Plus Prednisone or Mitoxantrone Plus Prednisone for Advanced Prostate Cancer: Updated Survival in the TAX 327 Study Mitoxantrone, vinorelbine and prednisone (MVD) in the treatment of chemotherapy; hormone resistance; mitoxantrone; prostate cancer; vinorelbine. Received 17 April 2003; revised 10 September 2003; accepted 24 September 2003 Dawning of the Age of Chemotherapy for Prostate Cancer Indeed, until recently the only US Food and Drug Administration-approved chemotherapeutic regimen for prostate cancer, mitoxantrone and prednisone, Prostate Cancer and Prostatic Diseases - Mitoxantrone, vinorelbine Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with BBC NEWS | Health | Drug hope in prostate cancer care Men with advanced prostate cancer that is not responding to hormone Chemotherapy based on a drug called mitoxantrone can be used to relieve pain, Research into treatments for prostate cancer We thought prostate cancer didn't respond very well to chemotherapy. But recent clinical trials using some well known drugs - mitoxantrone (mitozantrone) Chemo Extends Life in Advanced Prostate Cancer - National Cancer Chemotherapy with the drugs prednisone and mitoxantrone has been shown to reduce pain in men with advanced prostate cancer that has spread to the bones, Mitoxantrone and Prostate Cancer Chemotherapy mitoxantrone is a prostate cancer chemotherapy drug. NEJM -- Docetaxel plus Prednisone or Mitoxantrone plus Prednisone Background Mitoxantrone plus prednisone reduces pain and improves the quality of life in men with advanced, hormone-refractory prostate cancer, Chemotherapy | Prostate Cancer Information | UPMC Cancer Centers Mitoxantrone is extremely well-tolerated and clearly offers symptomatic improvement in many men with advanced prostate cancer. Unfortunately, it is still |
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