Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

metastatic prostate cancer to bone
Serial Markers Of Bone Turnover In Men With Metastatic Prostate
UroToday.com- Presently, bone imaging to include bone scans is used to determine the progression of prostate cancer (CaP) metastatic to bone.

ACS :: How Is Bone Metastasis Treated?
Osteoblastic metastases occur most frequently in prostate cancer that has . when x-rays show the metastatic cancer is causing the bone to become thinner

Kiâ“67 Index in Metastatic Prostate Cancer
Objective: Prostate cancer in bone is generally thought to progress more rapidly than metastatic deposits of untreated prostatic cancer were obtained.

Laboratory Investigation - An orthotopic metastatic prostate
At high magnification, H&E-staining (Figure 7b) shows that the metastatic human prostate cancer cells in a bone lesion had histologic and cytologic features

IngentaConnect Bone and prostate cancer cell interactions in
Bone and prostate cancer cell interactions in metastatic prostate cancer. Authors: Vela, Ian; Gregory, Laura1; Gardiner, Edith M.; Clements, Judith A.1;

Nature Clinical Practice Urology | Should patients with prostate
Evidence indicates that prostate cancer bone metastases are partially . trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial).

Bisphosphonates in Metastatic Prostate Cancer
The results of this study are encouraging for the use of 186Re-etidronate for the management of bone pain from metastatic prostate cancer.

Overexpression of Cyclin D1 Is Associated with Metastatic Prostate
D, metastatic prostate cancer to bone displaying a positive. immunophenotype in the nulcei of the majority of invasive tumor cells.

Urology : MP-17.09: Serum chromogranin A in bone metastatic
MP-17.09: Serum chromogranin A in bone metastatic prostate cancer: comparison with prostatic specific antigen. A. Bantis1, A. Zissimopoulos2, C. Kalaitzis1,

Overexpression of Cyclin D1 Is Associated with Metastatic Prostate
Overexpression of Cyclin D1 Is Associated with Metastatic Prostate Cancer to Bone1. Marija Drobnjak2, Iman Osman2, Howard I. Scher, Melissa Fazzari and

The Journal of Urology : PROLONGED SURVIVAL WITH METASTATIC
Although prostate cancer is well known to have a prolonged natural history, this is generally not true for prostate cancer metastatic to the bone.

Advanced Prostate Cancer: Understanding Prostate Cancer Metastasis
Metastatic disease refers to prostate cancer that has left the prostate gland and its neighboring organs. Advanced prostate cancer bone metastasis and lymph

Hormone-Refractory Prostate Cancer with Bone Metastases - Prostate
However, even in a patient with prostate cancer, not all areas of enhanced uptake on bone scan are associated with metastatic disease, particularly in the

The Prostate Cancer Charity - First National Survey
For a man with prostate cancer there is a risk that the cancer will spread to the skeleton, causing metastatic bone disease. This can cause complications,

Treatment of advanced prostate cancer, from the Prostate Cancer
M1 disease is often associated with bone pain, which is a consequence of the growth of metastatic prostate cancer in the bone, placing pressure on the

Osteoblasts in Prostate Cancer Metastasis to Bone
Replacement of haematopoietic tissues in the bone marrow by the metastatic prostate cancer cells leads to anaemia and increases the susceptibility to

Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource
Routine periodic examinations and bone scans should be performed on a patient with metastatic prostate cancer. The goal is to prevent the progression of a

Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource
Patients with metastatic bone tumors do not need to lose hope, tumor survival, accounting for the high rate of prostate cancer metastasis to the spine.

eMedicine - Prostate Cancer: Metastatic and Advanced Disease
Manifestations of metastatic and advanced prostate cancer may include anemia, bone marrow suppression, weight loss, pathologic fractures,


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