Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

metastatic prostate cancer prognosis
UroToday - EAU 2006 - ABST 1061 Men with poor-prognosis non
Data used were from long-term follow-up (>5 yrs) randomized trials of poor-prognosis non-metastatic prostate cancer (cN0, cM0, and either Gleason score >8;

Response of Prostate-Specific Antigen after Androgen Withdrawal
Reynard IM, Peters TJ, Gillatt D: Prostate-specific antigen and prognosis in patients with metastatic prostate cancer - A multivariable analysis of prostate

National Library for Health - News & RSS Article
The review reported that goserelin improved survival in men with poor-prognosis, non-metastatic prostate cancer when administered alongside surgery or

NeLM - Adjuvant androgen deprivation therapy â˜curativeâ™ for poor
They propose an amended definition for cure specific to prostate cancer - treatment hormonal therapy for poor-prognosis non-metastatic prostate cancer,

Neurologic Complications of Prostate Cancer - May 1, 2002
Because neurologic complications of metastatic prostate cancer require prompt . Brain metastasis is associated with a poor prognosis. Once prostate

IngentaConnect Tissue factor expression and prognosis in patients
Tissue factor expression and prognosis in patients with metastatic prostate cancer. Authors: Akashi T.; Furuya Y.; Ohta S.; Fuse H.1

Urology : MP-17.04: Chemokine receptor CXCR4 expression and
MP-17.04: Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer. T. Akashi1, 2, K. Koizumi2, K. Tsuneyama3,

European Urology Supplements : MEN WITH POOR-PROGNOSIS NON
MEN WITH POOR-PROGNOSIS NON-METASTATIC PROSTATE CANCER CAN BE CURED WITH ADJUVANT ANDROGEN DEPRIVATION THERAPY. P. Mulders, T. Keane, N. Fleshner,

Prostate Cancer, The Cancer Information Network
Atlas of prostate is included. Understanding Prognosis and Cancer Statistics Prostate Cancer - When locally advanced or metastatic prostate cancer has

Prostate Cancer Treatment and Prognosis
Metastatic prostate cancer shows strong E-cadherin expression as .. Pelvic lymph node metastases in prostate cancer (PCa) carry an ominous prognosis.

Clinical study on prognosis of metastatic prostate cancer based on
bone metastasis as evaluated on bone scan and prognosis of metastatic prostate. cancer. Patients and methods. Fifty-eight patients with prostate cancer with

All About Prostate Cancer
Certain factors affect prognosis (chance of recovery) and treatment options. Prostate cancer is . Metastatic prostate cancer often spreads to the bones.

Risk Factors / Prognosis: How bad is my prostate cancer?
Family history, A family history of brothers or a father with metastatic prostate cancer can mean your cancer might be more aggressive

Prostate Cancer and Prognosis: Role of PSA
The role of PSA changes in predicting prognosis in patients with metastatic prostate cancer who are treated with androgen withdrawal therapy has also been

Evaluation of the prognosis of cancer patients with metastatic
Key words: bone scintigram - metastatic cancer - prognosis - survival time . In patients with metastatic prostate cancer, Soloway et al.

Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource
Skeletal metastases are also generally associated with poor prognosis. The overall failure rate of metastatic prostate cancer alone was 10%.

Classification of Prostate Cancer â“ TNM staging, gleason grading
The prognosis for patients diagnosed with prostate cancer critically depends on with metastatic disease have the lowest predicted survival rates of all.

eMedicine - Prostate Cancer: Metastatic and Advanced Disease
For metastatic prostate cancer, radiation is also applied for palliative .. are the best nomogram for predicting prostate cancer spread and prognosis.

Prostate Cancer Prognosis â“ survival, clinical and pathological
Prostate cancer prognosis information, including survival, is poor and patients with metastatic disease have the lowest predicted survival rates of all.


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