Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

imrt margin prostate
Distinct effects of rectum delineation methods in 3D-confromal vs
IMRT treatment planning of prostate cancer . The planning target volume 1 (PTV 1) was generated with a 3D margin of 5 mm around the GTV.

Prostate Cancer Research Institute - Intensity Modulated Radiation
Use of portal images and BAT ultrasonography to measure setup error and organ motion for prostate IMRT: Implications for treatment margins.

Development of a simultaneous boost IMRT class solution for a
For both phases, the MLC leaves were fitted using a penumbra margin of 6 mm in . As discussed previously, the minimum dose to the prostate for the IMRT

Prostate Cancer
3-D Conformal and IMRT prostate plans allow for approximately 5-millimeters of dose margin around the posterior (back edge) aspect of the prostate.

The impact of interfraction prostate displacement to CRT and IMRT
The PTVs included prostate with a margin (10 mm in posterior and 15 mm in other Conclusions: Underdosage is larger for IMRT than CRT. Prostate

Prostate cancer treatment, prostate cancer brachytherapy - dattoli.com
More patients with prostate cancer have been treated with IG-IMRT at Dattoli Cancer not only into the prostate, plus a carefully delineated margin,

IngentaConnect Dosimetric effects of patient rotational setup
However, the degradation was not significant for the three-phase sequential boost prostate IMRT technique and for the margin sizes used in our institution.

IMRT
Because the margins of IMRT are so tightly controlled, we can actually increase set ups are particularly important when treating cancer of the prostate.

IMRT - Is there an advantage!
To cover these you need a margin of space around the prostate. .. I say again that I see no inherent advantage to IMRT for prostate cancer.

PROSTATE CANCER - Treatment Options - IMRT
In response to this need, the IMRT high-dose radiation volume may be made to conform to the prostate +/- seminal vesicles plus a specified margin,

The impact of daily shifts on prostate IMRT dose distributions
The impact of daily shifts on prostate IMRT dose distributions . This uncertainty has been accounted for in the choice of PTV margin.

Dosimetric effects of patient rotational setup errors on prostate
setup uncertainties for different prostate IMRT techniques. They found that their one-phase. IMRT technique (1 cm CTV-to-PTV margin) and two-phase

ScienceDirect - International Journal of Radiation Oncology
Hypofractionated IMRT boost for prostate carcinoma with on-line targeting of the prostate gland: patient-specific PTV margins and acute toxicity results

Intensity-Modulated Radiotherapy (IMRT) of Localized Prostate Cancer
Guckenberger M,Flentje M.Review IMRT Prostate Cancer .. tion on margins for prostate radiotherapy. Int J Radiat Oncol Biol Phys. 2006;65:548Á“53.

ScienceDirect - International Journal of Radiation Oncology
As an example, when prostate 3D-CRT was being employed, often times one added a Áœ2-cm margin to the prostate.Á« So, in the move to IMRT where we feel


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